2026-10-27T00:19:28Z https://nostr.now Redish Lab https://nostr.now/npub16jr6tn76pth8u36wjh0j09zmed42aue7slg8er9nw3qtl6wuh3us8cknep https://media.neuromatch.social/accounts/avatars/109/604/522/652/944/553/original/526f9a2bc7df5e66.png https://media.neuromatch.social/accounts/avatars/109/604/522/652/944/553/original/526f9a2bc7df5e66.png https://nostr.now/nevent1qqs8lptzq06g29zar5mn7pk9l0fwr9w8hd02nqzcfqq2fx2nprke7hczyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78jqtm6qn Asking the neuroscience community here. Trying to find an article...<br/><br/>There was an article in around the year 2000 or so that was a review of the LTP brain slice literature in the previous decade. It had a table which I vividly remember that was three columns: column 1 was the molecule, column 2 was the journal it was identified as being involved, and column 3 was the journal it was refuted in. The citations were not just numbers. The point of the table was that column 2 was all glamour mags and column 3 were not. And then I remember this snarky sentence that was something like ... &#34;the reliability of the result is inversely related to the Nature of the Science involved&#34; with &#34;nature&#34; and &#34;science&#34; in italics. I think it was PNAS or TINS or the like. But I can&#39;t find it! This is driving me crazy. Any suggestions much appreciated!<br/><br/>I&#39;m obviously misremembering something (the journal, the authors, the date, maybe even the topic?). Does anyone have any idea what I&#39;m remembering?<br/><br/>PS. Importantly, the article I am thinking of is not Sanes and Lichtman NNsci 1999, which is what all my searches (normal websearch, personal journalsearch, and AI) are pushing. The page format is completely different. <br/><br/>#LTP #neuroscience #replicability 2026-10-03T13:15:17Z https://nostr.now/nevent1qqsfxsuklnavfzush38m3lzjex8kaze082etrvx9yrye0w7audp3lkczyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78jf8svq3 In reply to <a href='/nevent1qqsqf2w8ljgua5av2s8qy4kmsxc0ayhmlj6h0wfypnnjwu0zfwhwwcsw0zr6d'>nevent1q…zr6d</a><br/>_________________________<br/><br/>💯 Even if the GPT model provides a valid reference, if you don&#39;t engage with it, you are not doing scholarship. <br/><br/>When I teach students, I tell them that they should never cite anything they haven&#39;t actually read, or even better read and re-read.<br/><br/>It&#39;s very disappointing (although not surprising) to find that the editors of these GlamourMagz are doing bad scholarship. (Most of the click-bait news-journalism parts of these magazines has been crap for decades and has actively damaged the scientific enterprise.) 2026-07-18T10:52:09Z https://nostr.now/nevent1qqsyds4575su4g2t8l9grjtzd5fwpld8nwyftfdn9pdktmcshmjuhgqzyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78j5n0nq2 An absolutely fascinating article on the self-destruction of the American Hegemony and the implications for software technology around the world.<br/><br/>Found from <span itemprop="mentions" itemscope itemtype="https://schema.org/Person"><a itemprop="url" href="/npub1fdrpydz4n2dpgpy5xhsa6rjg8ytggn82mt0addw6sf93272nhhnqsjlvhs" class="bg-lavender dark:prose:text-neutral-50 dark:text-neutral-50 dark:bg-garnet px-1"><span>Cory Doctorow</span> (<span class="italic">npub1fdr…lvhs</span>)</a></span> &#39;s recent blog post. (Which is always worth reading.)<br/><br/><a href="https://www.baldurbjarnason.com/2026/the-old-world-of-tech-is-dying/">https://www.baldurbjarnason.com/2026/the-old-world-of-tech-is-dying/</a> 2026-05-16T11:54:31Z https://nostr.now/nevent1qqs0xeryjcvnxd5mfuh2vrzgtvqm8dsft22ehyms9schpncz5rf6m7czyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78jumzjtc In reply to <a href='/nevent1qqsdjpv75l74mkv7agud8qy63mhjpswnkhvv33mgrg5n3f8mfjnsgvc2x2srg'>nevent1q…2srg</a><br/>_________________________<br/><br/>One of my colleagues (Steve Kelley) had a very helpful perspective on this. He said that one should always engage with politicians (and other activists) knowing which of three hats you were wearing:<br/><br/>Hat 1. This is my expertise. I am the world expert in this topic. It comes from my research and I am *the* person to talk to about this topic.<br/><br/>Hat 2. This is my field. I know the nuances and questions that one needs to ask. I&#39;m qualified to tell you which science is well-founded and which is bogus.<br/><br/>Hat 3. I&#39;m a citizen. I&#39;m a reasonably smart person who wants to share my opinions on what one should do in this situation.<br/><br/>I&#39;ve found that talking to politicians being explicit about which hat I&#39;m wearing has been very helpful. (And all three hats can be important. Remember, politicians want to know what their constituents want ... well, good politicians do. This why &#34;call your representative&#34; matters.)<br/><br/>Steve knows from what he is talking about. He was a state senator here in MN and then transitioned to be faculty in our School of Public Affairs. He ran a class once for other faculty in engagement, which is where I got this from. 2026-03-05T13:08:01Z https://nostr.now/nevent1qqsds6sp6kuqg2qkeknxhrg9jdpfwnfz6rlyp874usdakarzaxm6rqqzyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78j8xztcd In reply to <a href='/nevent1qqs0nml8nzrf5jmltalnjk7xm7zt8aucp7wjw0p8mss2my7cs2utnmgr3hulj'>nevent1q…hulj</a><br/>_________________________<br/><br/>I think this is a good idea. <br/><br/>Anyone who wants a grant has to do at least 3 reviews for each submission. Anyone who wants to publish a paper has to do at least 2 reviews for each submission. <br/><br/>Not only would that help the review backlog, it would help limit the people who submit way too many grants and papers. 2026-03-02T15:56:28Z https://nostr.now/nevent1qqs8hygk35dr5pq75elmfm6kdut20729xpnjme4clsc4acgaejr8vkszyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78jj5ljrg In reply to <a href='/nevent1qqs949ng82vt6gkrawft2ceuq0tu9x3rajhse9pcwwtqg2nd66pz2rquqz2zl'>nevent1q…z2zl</a><br/>_________________________<br/><br/>That perspective makes me terribly sad. Science should be about communication and community. Tell everyone about all of your ideas because their dialogue will make your ideas better.<br/><br/>Moreover, there is room for all of us. We need to remember that the problem isn&#39;t that there isn&#39;t enough science funding for all the positions. The problem is that we have given all of our money (including all of our science money) to a handful of billionaires. (Apparently so that they can fuck up our politics and our society.)<br/><br/>And before someone says &#34;there&#39;s no political will for this&#34;, I would point out that political will changes over time. Don&#39;t give in to their arguments.<br/><br/>If you&#39;re going to fight for something, fight for enough science budget that anyone who wants can do the work that helps the world be better. Don&#39;t fight to kick people out of this community just because they are older (or because of their skin color or their gender or any other unrelated-to-the-science-they-are-doing characteristic). 2026-01-29T13:16:37Z https://nostr.now/nevent1qqs2meydvq4sdufrhsays2a8ex8hy7x2uy7rv8v5vam7lh967wzdhcgzyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78jnfmdkr Found out my kid uses #spotify I want to recommend an alternative. What&#39;s the best alternatives to suggest to them? thx.<br/><br/>Adding #BoycottSpotify because I assume people following that hashtag will know other options. 2025-12-30T23:22:14Z https://nostr.now/nevent1qqsd0jnjnay63cl53znlexguazx5z7zgew6t407vvavluv0gl40ge5czyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78jwf6v5e In reply to <a href='/nevent1qqs8kdnnt5qhpah6l98753lm3fj46fnl6cfg3yezrcy8k2gy4lqk33qzxcxum'>nevent1q…cxum</a><br/>_________________________<br/><br/>This is classic corporate responses to academia.<br/><br/>I once was visiting London for a conference, mentioned this to a former student who was (at the time) working at DeepMind (I think it was part of Google then, but don&#39;t remember). He suggested I give a talk, and I said sure. They wanted me to I sign an NDA as &#34;standard practice when someone visits DeepMind&#34;.<br/><br/>I told them I do not sign NDA&#39;s on principle. (I don&#39;t believe they are ethical. Also, I&#39;m terrible at keeping secrets. :) I told them that I was on the outside and that anything they told me was public. They said &#34;then you can&#39;t meet our people&#34;. I told them that was their loss not mine.<br/><br/>PS. The eventual outcome was that they did have me give the talk. I met lots of great people and we had great conversations about both the work I do and what they were working on. So ¯\_(ツ)_/¯. No, I did not sign an NDA. 2025-12-06T13:13:59Z https://nostr.now/nevent1qqsydkejya3qg8lmasxt8skcdpt0p3u7e4chlcqw93w8fcz64x03ulczyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78j6q5009 ICE is apparently in Minneapolis raiding buildings. 2025-12-03T15:17:53Z https://nostr.now/nevent1qqsp80e0j80tf2g83dtwcywrldmucrj2lhgzekekqrry7aj605n64kszyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78jj7v628 [@knutson_brain](<a href="https://sfba.social/@knutson_brain">https://sfba.social/@knutson_brain</a> ) <br/><br/>You were right and I was wrong. <br/><br/>#Wikipedia works because it has a central set of sources that it accepts. One can only add a fact if there is a source that is real, cite-able, and reliable. Moreover, what Wikipedia promises is not &#34;X is true&#34;, but rather &#34;Z says X is true&#34;. This must be verifiable and Z must be a reliable source. <br/><br/>So Wikipedia does have a restriction process like peer-review (although it is different).<br/><br/>See the excellent (as always) discussion by <span itemprop="mentions" itemscope itemtype="https://schema.org/Person"><a itemprop="url" href="/npub1fdrpydz4n2dpgpy5xhsa6rjg8ytggn82mt0addw6sf93272nhhnqsjlvhs" class="bg-lavender dark:prose:text-neutral-50 dark:text-neutral-50 dark:bg-garnet px-1"><span>Cory Doctorow</span> (<span class="italic">npub1fdr…lvhs</span>)</a></span>: <a href="https://pluralistic.net/2025/09/05/be-the-first-person/">https://pluralistic.net/2025/09/05/be-the-first-person/</a><br/><br/>1/2 2025-09-07T21:19:04Z https://nostr.now/nevent1qqsq2fczzcln4sdek2es2qs2kmmk59ppgttw7uhh99emlzf2k66yafczyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78jz87jww There were two things that made America the economic powerhouse that it is. One was the innovation and hard work we got from immigration. The other was the enormous federal spending on science independent of its potential immediate relevance, which generated novel innovations. The key to both of these is the huge long-term gains, which manifest over the time-line of decades.<br/><br/>The current administration couldn&#39;t be doing more damage to the US if they actually were traitors and quislings.<br/><br/>😢 2025-08-13T13:09:08Z https://nostr.now/nevent1qqsw60xhh5hz0jz95jkwlz229expjmy270wygpvzk0dd0xqvnp2hdrgzyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78jk27355 An interesting thing that I realized in a response to <span itemprop="mentions" itemscope itemtype="https://schema.org/Person"><a itemprop="url" href="/npub1xnecvuwkje7ek757wy9e6wl64qyc2mzcc90l262rzvzyxhs9vmeqqkxqch" class="bg-lavender dark:prose:text-neutral-50 dark:text-neutral-50 dark:bg-garnet px-1"><span>Benoît Girard</span> (<span class="italic">npub1xne…xqch</span>)</a></span> and <span itemprop="mentions" itemscope itemtype="https://schema.org/Person"><a itemprop="url" href="/npub14c5eddu9ddulgvgh8zrk9mz954tw32zymd4h88aj27f0g8lddy3sa2rfvf" class="bg-lavender dark:prose:text-neutral-50 dark:text-neutral-50 dark:bg-garnet px-1"><span>Dan Goodman</span> (<span class="italic">npub14c5…rfvf</span>)</a></span>.<br/><br/>There are ~60k postdocs in the US. Assume a lab costs on average $500k/yr. 60k PD @ $500k/yr = $30b.<br/><br/>Giving EVERY current postdoc in the US a lab would require doubling the NIH budget, but not more than that. 🤯 <br/><br/>We just gave $300b/yr in tax cuts to the wealthy. 🫤 <br/><br/>I don&#39;t know EU numbers, but I assume they&#39;re similar. 2025-08-02T18:22:01Z https://nostr.now/nevent1qqsz80zl8za88z0kjww986u5uwpyrvle7a6r9d4lgmakcwyfmtajsyczyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78je735kn In reply to <a href='/nevent1qqsvty0yz3n9frcag98gnetu9g75r2f5y5xwzqj2azxeqjpz8kmp22gdp3gdp'>nevent1q…3gdp</a><br/>_________________________<br/><br/>I think it&#39;s also important to point out that these three techniques (agree - all are important!) sample different aspects of neural signalling. It&#39;s not just fidelity or scale. <br/><br/>Patch clamp measures in vivo voltage fluctuations, but those are not necessarily transmitted down axons, and you can have axonal generation of signaling. Electrode arrays (wires, tetrodes, silicon arrays, neuropixels) measure spikes (and LFPs, which are also a different signal, providing different information about the system). Calcium imaging provides information about calcium levels. <br/><br/>Although these signals are correlated with each other, they are not identical and should *never* be substituted one for the other. You can have calcium without spikes, synaptic interactions (intracellular signals) that do calculations, spikes without calcium, etc etc etc.<br/><br/>Instead of asking &#34;can we see replay with calcium signaling?&#34; I think we should ask &#34;what is the calcium signaling doing when hippocampal sequences are replaying?&#34; <br/><br/>That&#39;s why we need a literature. That&#39;s why we need all of these techniques. The information is synergistic. 2025-07-17T13:26:11Z https://nostr.now/nevent1qqsf5udtga47vs8jezg9gp2pw9thvfnrcvm2tc2ap70sa9x5awu0p7szyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78jz6zhj0 It&#39;s amazing how different economics looks when you assume the goal is to have an EFFECTIVE system rather than an EFFICIENT system.<br/><br/>An efficient system uses resources maximally, thus resources are never left lying around, but needs must be waiting for resources to become available.<br/><br/>An effective system resolves needs maximally, doing its best to ensure no needs are left unfulfilled. This requires that resources must be kept idle for unexpected needs.<br/><br/>In practice, effective systems are often more long-term efficient because emergency needs are often particularly expensive. 2025-07-11T20:14:26Z https://nostr.now/nevent1qqs23ljwsh88vjjk4d8qn07taczknfa7j8lu8cr5vwew0l7mlxpanvszyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78js98j0h In reply to <a href='/nevent1qqsz02r3zetzlzl8vkktuw0n7kvk5xxpfg2p4h668unl444tacmvleqqtk8d4'>nevent1q…k8d4</a><br/>_________________________<br/><br/>Why were non-US arXiv mirrors shut down? <br/><br/>what about the other rXiv&#39;s (bioRxiv, medRxiv, psyRxiv)? 2025-03-14T15:52:18Z https://nostr.now/nevent1qqsq0u8n2nksn6jykftg87tsrqmuraudg9v289p4hvnklvcry69sf7gzyr2g0fw0mg9wulj8f62a7fu5t09k4thn86raqlyvkd6yp0lfmj78j2smy4t As usual, <span itemprop="mentions" itemscope itemtype="https://schema.org/Person"><a itemprop="url" href="/npub1w888sy09tr9h6wlh67nlcczfhemvx54s3j3slxkndwa4y2yvhptqwwf8j6" class="bg-lavender dark:prose:text-neutral-50 dark:text-neutral-50 dark:bg-garnet px-1"><span>Nature</span> (<span class="italic">npub1w88…f8j6</span>)</a></span> misses a key factor in the story. While I agree with all of the points raised in this story (<a href="https://www.nature.com/articles/d41586-024-03906-0">https://www.nature.com/articles/d41586-024-03906-0</a>), it assumes that the government entities have the same GOAL as the science provides. But we know that many people in power do not have this same goal. We know that one of the reasons scientists are not asked to provide advice to governmental entities are that they give answers that people in power don&#39;t want to hear.<br/><br/>The survey in Figure 2 includes &#34;politicians don&#39;t understand science&#34; and &#34;misinformation obscures science advice&#34;, but it doesn&#39;t include &#34;politicians don&#39;t want to achieve the goals scientists provide&#34;.<br/><br/>Remember, the energy companies correctly predicted climate change (accurately! <a href="https://www.science.org/doi/10.1126/science.abk0063">https://www.science.org/doi/10.1126/science.abk0063</a>). It&#39;s not that they didn&#39;t understand the science. It&#39;s that they didn&#39;t want the outcome it would drive them to.<br/><br/>Note: unfortunately, half of the article is paywalled, but I got through to the rest of it from my institution and there&#39;s nothing particularly new in the last half. 2024-12-04T13:39:19Z