DrYak

Medical Doctor and Bioinformatician

ORCiD: https://orcid.org/0000-0002-7561-0810
GitHub: https://github.com/DrYak

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npub1glh2m4gj6zfutj7uzyusl8xzrk9tzfmam49t2c4t99suqc6uk9eq9zptpk

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nprofile1qqsy0m4d65fdpy79e0wpzwg0nnppmz43ya7a6j44v24jjcwqvdwtzuspz3mhxue69uhhyetvv9ujuerpd46hxtnfduqs6amnwvaz7tmwdaejumr0ds446emr

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nostr.wine

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Last Notes

2026-10-24 22:38:56 UTC

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this, by the way, is a good way to see the actual limits of nodern chat-bots: take a personnal hobby you're very good at and query the slop machine to extrude an explanation or answer for something non trivial that you know very well. Be prepared to be extremely disappointed. This is the same "quality" of "answers" the slop machines have been extruding each time you queried about something you're not fluent in, you merely didn't notice how much of a garbage the "answer" was.

2026-10-08 20:02:32 UTC

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Video game "vibewashing" is very active in practice. (Modern Vintage Gamer did a video recently on that: https://youtu.be/mYZPHdKKMaI).
A quick look on Quiver (https://quiverlauncher.com/) reveals quite a few recomps of Nintendo games, including big franchises like Mario and Zelda.
That these aren't getting lawyer-bombed into oblivion is quite revealing in my opinion, as if it was somewhat in the interest of by corporations that "vibewashing" remains legal.
[...]

2026-08-23 15:31:50 UTC

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...
Other projects try metagenomic approaches (listing everything they could detect).

2026-08-23 15:31:05 UTC

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Yup exactly.
Our projects specialise in tracking variants of specific viruses (useful for questions regarding vaccines, drug resistance, etc.)
Big advantage is that it samples a large population while being completely anonymised (we sample at the treatment plant level) is less biased (everybody shits and showers) and much cheaper than large scale population testing campaigns.
...

2026-08-23 05:59:00 UTC

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(side note: ...and we do gene sequencing on sewers.)

2026-07-14 16:20:05 UTC

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in the future, if again you find yourself needing more recent versions of software than Debian carries, it might be worth checking openSuse Tumbleweed.
It's a rolling distro (so very recent versions of everything), but the team at openSuse spends lots of time integrating everything together and running tests to ensure it's stable.
Compared to other rolling (e.g.: I run Arch Linux on other machines) it's much more stable.
Plus they don't force snap or AI.

2026-07-14 16:13:57 UTC

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reading your install guide, it's very interesting and I am finding a few useful tips even if not in the same field of work as you. Thanks for sharing!

2026-05-19 18:10:02 UTC

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"But that would tottaly be gay! (tm)" 🙃
(I swear, I've heard that stupid argument thrown at me)

2026-05-08 18:44:22 UTC

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Most recently AI - What's the point in encrypting everything end-to-end and then have the end-point stream all messages back to cloud servers running Meta's AI for summarising, "smart"-search and othe similar useless crap?
So yeah that E2EE is very "on paper theoretically", and in practice is mostly a marketing ploy to gain some user confidence avoid them switching, in the years after the scandals around Snowden blowing the whistle.

2026-05-08 18:39:51 UTC

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surpisingly: yes, mostly since reorganizing its direct messaging feature to rely on Facebook Messenger, which it self had incorporated the E2EE protocol from Signal, not long after doing the same with WhatsApp.
Though "E2E" is very relative - technically such scheme can only be trusted as much as said end-points - which is hard given than none of the Apps by Meta are open source.
And all these apps have a few extremely glaring holes:
...

2026-02-15 12:46:45 UTC

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(it's a Germanism.
In lots of languages the names themselves of animal are gendered. In German (and several slavic language) the word "cat" itself is a feminine gender noun.
So by default lots of German or East European would go "She's beautiful" (just like English people and ships).
BTW: how is it in Spanish? (it's masculine gender noun in the latin languages I know: French and Italian)

2026-01-18 12:52:47 UTC

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...
When you need those app, you can start the container, do stuff, then shut down.
The operating system I daily drive on my Linux phones (I run SailfishOS) offers something similar (Jolla calls their container "AppSupport») for the few apps I can't do without.

2026-01-18 12:52:05 UTC

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for the banking and other android apps, I would suggest looking into running Waydroid:
It's a container (roughly similar to docker) inside which you run some LineageOS (it's based on AOSP - the opensource bits of android) and install microG (open source reimplementation of the Google Play Services that lots of App rely upon) and Aurora (opensource reimplementation of Google Play Store)
...

2025-11-20 19:39:48 UTC

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...and that's assuming that the nukes are still functional.
It's a highly technical weapon.
And once you start to try restricting higher education to rich white failsons, try to cut funding to universities, and in general wage a "war on education", I am not sure how long you'll be able to have the necessary highly skilled workforce to keep the nukes functional.

2025-08-17 20:22:08 UTC

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...
just as you describe "google-bombs", link farms and the likes, the academic world has seen it's own abuses of citation based metric with citation farming, predatory journals.
As a recent example that attracted some attention during the pandemic: the french prof. Didier Raoult who turned out to have inflated his ranking by massively publishing low quality paper in journals headed by his acquittances and citing each others.

2025-08-17 20:20:41 UTC

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Please allow me to disagree:
imho Sergey Brin and Larry Page didn't really realise much: they merely reused the same kind of citation-based metrics that was all the rage in Academia for evaluating journals, researchers and institutions.
This could seem breakthrough to general public who only knew Yahoo, but PageRank is really just a very derivative "Impact factor, but on the INTERNET!"
So much so that both are susceptible to the same attacks:
...

2025-08-15 19:44:15 UTC

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part of the reason I still enjoy my 15 years old Dell Lattitude:
It has a mouse-stick and thus a set of button next to the space bar, very easy to reach without twisting.
Hopefully somebody will come up with something similar for your framework.

2025-07-09 20:10:19 UTC

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problems solved: it works mostly on its own. It takes 5h instead of 2h as it's less efficient, but it's 5h during which I don't even need to be in the house (or could work).
Bonus: as most of these robots are flat, they easily vacuum under furniture.
Even more useful if you own pets and need to vacuum the shedded fur daily.
But result will depend on the clutter, the amount of furniture blocking the way, the algo used by manufacturer / gen, and extras like self-cleaning

2025-06-16 18:33:37 UTC

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As you mention switching to FOSS next time you need to go throught the same ordeal:
I would recommend considering ThunderBird for e-mail and in perculiar the TbSync and EAS-4-TbSync addons to handle connecting tp Exchange mail aervers.
Both academic institutions I work with switched to MicroSoft 365 and these addons have saved me to keep accessing Calendats etc.

2025-06-06 18:29:36 UTC

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(I am so happy to be living in a country that values and invests into its public transport infrastructure --- in addition to valuing its direct democracy)

2024-11-13 21:01:50 UTC

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AOSP itself is fully open source, but not a complete Android distro.
One also needs:
1- drivers which usually come as proprietary blobs (on a myriad of additional partitions)
2- additionnal services and API that most apps rely on, usually Google's proprietary Play Services (though there's microG, an open source implementation of the same API)
(and obviously apps, but here F-Droid can provide some alternatives)

2024-11-12 12:31:48 UTC

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are you using something like Bridgy Fed? Or are you managing Bs and Mastodin separately.

2024-11-10 12:19:40 UTC

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and 5 years down from now: "now that extremists/tech-bro/enshittification have taken over Bluesky, here's how to migrate to Mastodon". 🙃
(yes, specially since the latest investments, I don't trust the ATmosphere to ever fully decentralize and federate).

2024-10-21 23:53:12 UTC

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the container boxes that go in the cargo hold (Wikipedia tells us the official name is "unit load device (uld)") that I've seen seem most often made of metal (aluminium) and thus already poorly transmitting BLE signals.
No need to add weight (and waste fuel) further to block tags.

2024-08-15 12:02:50 UTC

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in my experience with editing code on a chromebook-class Linux laptop (PineBook Pro) even the simpler Kate has enough bells and whistles for most common tasks (e.g.: syntax highlighting).
Regarding RAM: it might be worth looking into Zswap (a compressed cache that stand between you app's RAM and the actual swap on disk).