I'm want to push back a bit on the initial framing. The scope of "Python packaging" is much wider than the pip/wheel ecosystem.
Conda and Linux distro packaging is as or more important in practice (in some domains).
See https://pypackaging-native.github.io/ for some of the technical and social issues with pip/wheel.
An even hotter take: language specific package managers are doomed to either become general package managers or not be fit for purpose.