I think the concept of "Technoculture" is useful: https://en.wikipedia.org/wiki/Technoculture
Responding to the question "Why are people mean on Twitter?", would it make sense to say that's a cultural problem and not a technical one? Would it make sense to say that's a technical problem and not a cultural one? It's obviously both and they both affect each other. Technology and culture are dialectical, not dichotomous.