The GO bell speeds up its maker; more couriers = louder "release."
But insulin runs a shredder (PDE-3B) that destroys couriers.
So eating doesn't just go quiet, it actively erases the signal. Two off-switches, one go-switch
Raghav Agrawal on Nostr: How does a doorbell on the outside reach machinery on the inside? A courier molecule: ...
How does a doorbell on the outside reach machinery on the inside? A courier molecule: cAMP.
The GO bell speeds up its maker; more couriers = louder "release."
But insulin runs a shredder (PDE-3B) that destroys couriers.
So eating doesn't just go quiet, it actively erases the signal. Two off-switches, one go-switch
The GO bell speeds up its maker; more couriers = louder "release."
But insulin runs a shredder (PDE-3B) that destroys couriers.
So eating doesn't just go quiet, it actively erases the signal. Two off-switches, one go-switch