Weekend Editor on Nostr: nprofile1q…nxfq3 I once had collaborators who wanted to measure expression, copy ...

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I once had collaborators who wanted to measure expression, copy number, and mutation data on a wide variety of cancers and normal tissues.

Laudable, so far.

BUT: they insisted on processing them in a priority order, according to the priority of internal projects.

That meant: batch effects were convolved with organ effects, more or less impossible to tease apart.

Of course they blamed the uncooperative bioinformaticists (who had warned them about this in the beginning).