Not always. I have to stay away from my family, cos they still hope (think) I made a mistake, and maybe one day I realise this and go back. I've not spoken to my mum, for a year and a half now. 21 years transitioned, and cos I mentioned my depression was ticking up again the other year, she was back with the "hopeful" question of did I think I'd made a mistake.
Fuck . That. Shit.
So no, just cos people know trans folk, doesn't mean they'll come out to bat for them.