smallworlnd on Nostr: I'm not an expert on cell cycle stuff, and especially not in humans but my general ...

I'm not an expert on cell cycle stuff, and especially not in humans but my general understanding is that whatever the state the cell might be in to trigger telomere maintenance, it subsequently triggers a DNA integrity check and a "decision" as to what to do thereafter, like damage response and cell fate. Telomere maintenance is complicated machinery composed of many different proteins and functional RNAs, including telomerase, which interacts with a number of pathways to regulate itself. I just wouldn't know if your hypothesis is reasonable.