One of the first things neutron transmutation was used for was to convert gold into mercury.
Perhaps you're wondering why. The reason is that Au is monoisotopic (197), but natural Hg is not. The US Bureau of Standards wanted monoisotopic Hg for its sharp spectral lines. So in 1939 they shipped a quantity of the US Treasury's gold reserve to California, to be bombarded with neutrons from the big Berkeley cyclotron. Later it was sent to Oak Ridge, to the X-10 pile.