'Severe asthma can be controlled by a monthly injection, trial finds'
"While most can control their asthma with inhalers to treat immediate symptoms and preventive ones to reduce inflammation, those with the most severe asthma often take daily doses of oral corticosteroids as well."
"But long-term use is associated with serious health conditions, including osteoporosis, diabetes and increased vulnerability to infections."
"Now an international clinical trial has found that participants who received injections of tezepelumab every four weeks were able to reduce or even stop taking their steroids entirely with no ill effects."
"The Wayfinder trial, led by Kings College London, involved just under 300 adults with severe, uncontrolled asthma, who were taking 5mg-40mg of steroid tablets daily.
The patients, from 11 countries including the UK, US, France, Germany, Mexico and Spain, were given tezepelumab every month."
https://www.theguardian.com/society/2025/nov/26/severe-asthma-controlled-monthly-injection-tezepelumab-trial-finds
The study:
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00359-5/fulltext
#health #Asthma #trial #tezepelumab
Omega_Scribet
npub1qv…r7pch
2025-11-27 11:19:29 UTC
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2025-11-27 11:19:29 UTCEvent JSON
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"content": "'Severe asthma can be controlled by a monthly injection, trial finds'\n\n\"While most can control their asthma with inhalers to treat immediate symptoms and preventive ones to reduce inflammation, those with the most severe asthma often take daily doses of oral corticosteroids as well.\"\n\n\"But long-term use is associated with serious health conditions, including osteoporosis, diabetes and increased vulnerability to infections.\"\n\n\"Now an international clinical trial has found that participants who received injections of tezepelumab every four weeks were able to reduce or even stop taking their steroids entirely with no ill effects.\"\n\n\"The Wayfinder trial, led by Kings College London, involved just under 300 adults with severe, uncontrolled asthma, who were taking 5mg-40mg of steroid tablets daily.\nThe patients, from 11 countries including the UK, US, France, Germany, Mexico and Spain, were given tezepelumab every month.\"\n\nhttps://www.theguardian.com/society/2025/nov/26/severe-asthma-controlled-monthly-injection-tezepelumab-trial-finds\n\nThe study:\nhttps://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00359-5/fulltext\n\n#health #Asthma #trial #tezepelumab",
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